Across TCGA pan-cancer cohorts, SEPTIN7P2 Mutation is linked to patient survival in 3 of 34 cancer types, making it a survival-associated SEPTIN7P2 data layer compared with 25 for mass-spec protein.

The strongest signal is observed in skin cutaneous melanoma (SKCM), where higher SEPTIN7P2 Mutation is associated with worse disease-free survival. In most high-consensus cancer types, elevated SEPTIN7P2 expression acts as an unfavorable survival marker.

SKCM, BRCA, and LIHC are the cancer types where SEPTIN7P2 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
SKCM	DFS	Median	All	0.015	0.758	<.001	18	view →
BRCA	OS	Median	All	0.107	0.578	<.001	12	view →
LIHC	OS	Median	All	0.144	0.688	.013	9	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

Exploration

Same gene, other analysis: SEPTIN7P2 tumor-vs-normal RNA expression · all SEPTIN7P2 data types