SEPTIN7P2

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, SEPTIN7P2 mutation is significantly associated with the RNA expression of many other genes, with 402 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SEPTIN7P2-associated genes across cancer lineages are SEC13, SSTR5, and SAP30. Each is linked with SEPTIN7P2 in more than 1 cancer types. Because this analysis shows association rather than direction, both SEPTIN7P2-to-partner and partner-to-SEPTIN7P2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SEPTIN7P2→partner) and Y-score (partner→SEPTIN7P2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECSEC13 →+0.558+3.210.001.00931
UCECSSTR5 →+0.890+3.897<.001<.00131
UCECSAP30 →+0.788+3.343.002.00531
UCECSTOML2 →+0.587+3.212.006.00931
UCECUBXN6 →+0.477+3.343.006.00531
UCECPOLR2G →+0.523+3.233.005.00931
Each partner links to its Q-omics profile. Showing the 6 strongest of 402 associations by consensus.

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