Across TCGA patient cohorts, SEPTIN7P2 mutation is significantly associated with the total protein of many other genes, with 5 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SEPTIN7P2-associated genes across cancer lineages are Notch1, STAT3_pY705, and Caspase-8. Each is linked with SEPTIN7P2 in more than 1 cancer types. Because this analysis shows association rather than direction, both SEPTIN7P2-to-partner and partner-to-SEPTIN7P2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SEPTIN7P2→partner) and Y-score (partner→SEPTIN7P2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Notch1 →	+0.174	+3.169	.024	.020	3	1
UCEC	STAT3_pY705 →	-0.523	-3.169	<.001	.020	2	1
UCEC	Caspase-8 →	-0.292	-3.000	.034	.036	2	1
UCEC	4E-BP1 →	+0.524	+2.837	<.001	.035	2	1
UCEC	MEK1 →	+0.517	+3.169	.010	.020	1	1

Each partner links to its Q-omics profile. Showing the 5 strongest of 5 associations by consensus.

Exploration

SEPTIN7P2 survival (RNA) · tumor vs normal (RNA) · all SEPTIN7P2 data types