SEPTIN7P12

Across TCGA pan-cancer cohorts, SEPTIN7P12 RNA differs between tumor and matched normal tissue in 7 of 18 cancer types tested, making tumor–normal expression one of SEPTIN7P12’s most consistent transcriptional readouts.

The strongest signal is observed in stomach adenocarcinoma (STAD), where SEPTIN7P12 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types SEPTIN7P12 is over-expressed in tumor, although a few such as THCA show the opposite, repressed pattern.

STAD, BRCA, and LUAD are the cancer types where SEPTIN7P12 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in SEPTIN7P12 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
STAD	All	II,III,IV	+0.226	.012	4	view →
BRCA	Female	II,III,IV	+0.184	.015	4	view →
LUAD	All	All	+0.252	.027	2	view →
LUSC	Male	All	+0.064	.034	2	view →
COAD	Female	II,III,IV	+0.064	.041	2	view →
THCA	Male	All	−0.055	.004	2	view →
ESCA	Female	All	+0.496	.027	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 7 strongest of 7 lineages.

SEPTIN7P12–STAD

Open the STAD breakdown →