SEPTIN7P10

Across TCGA pan-cancer cohorts, SEPTIN7P10 RNA is linked to patient survival in 22 of 34 cancer types, making it the most broadly survival-associated SEPTIN7P10 data layer.

The strongest signal is observed in thymoma (THYM), where higher SEPTIN7P10 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated SEPTIN7P10 expression acts as an unfavorable survival marker, although some lineages such as OV and COAD show a favorable association.

THYM, HNSC, and STAD are the cancer types where SEPTIN7P10 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
THYM	OS	Quartile	II,III,IV	0.740	1.000	<.001	47	view →
HNSC	DFS	Tertile	All	0.392	0.626	.001	38	view →
STAD	OS	Quartile	III,IV	0.277	0.717	.004	36	view →
ACC	DFS	Quartile	III,IV	0.326	0.540	.021	21	view →
KIRP	DFS	Tertile	IV	0.036	0.458	.035	19	view →
OV	OS	Median	III,IV	0.874	0.802	.002	18	view →
LGG	OS	Tertile	All	0.825	0.926	.004	16	view →
KIRC	OS	Tertile	All	0.498	0.686	.001	15	view →
DLBC	OS	Quartile	All	0.546	0.879	.010	12	view →
COAD	OS	Tertile	IV	1.000	0.329	.016	9	view →
CHOL	OS	Median	All	1.000	0.347	.029	9	view →
LUAD	OS	Quartile	III,IV	0.771	0.416	.018	8	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 22 lineages.

SEPTIN7P10–THYM (OS)

Open the THYM breakdown →