SEPTIN6

Across TCGA patient cohorts, SEPTIN6 RNA expression is significantly associated with the protein abundance of many other proteins, with 15,747 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible SEPTIN6-associated proteins across cancer lineages are ANKRD44, DOCK11, and WIPF1. Each is linked with SEPTIN6 in more than 9 cancer types. Because this analysis shows association rather than direction, both SEPTIN6-to-partner and partner-to-SEPTIN6 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SEPTIN6 versus ANKRD44 in OV, with a Pearson correlation of 0.43.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SEPTIN6→partner) and Y-score (partner→SEPTIN6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	ANKRD44 →	+0.463	+0.972	.003	.002	3	10
OV	DOCK11 →	+0.701	+1.221	<.001	<.001	3	10
UCEC	WIPF1 →	+0.463	+0.628	<.001	<.001	3	9
GBM	RASAL3 →	+0.478	+0.618	<.001	<.001	3	9
GBM	LPXN →	+0.638	+0.506	<.001	<.001	3	9
HNSC	ARHGAP25 →	+0.593	+0.556	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,747 associations by consensus.

SEPTIN6 vs ANKRD44 — OV

Explore this scatter interactively →