SEPTIN6

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, SEPTIN6 protein abundance is significantly associated with the protein abundance of many other proteins, with 25,876 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible SEPTIN6-associated proteins across cancer lineages are ARHGEF6, PTPN7, and RAC2. Each is linked with SEPTIN6 in more than 8 cancer types. Because this analysis shows association rather than direction, both SEPTIN6-to-partner and partner-to-SEPTIN6 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SEPTIN6 versus ARHGEF6 in LSCC, with a Pearson correlation of 0.85.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SEPTIN6→partner) and Y-score (partner→SEPTIN6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LSCCARHGEF6 →+0.630+0.634<.001<.00139
LSCCPTPN7 →+0.649+0.609<.001<.00139
OVRAC2 →+0.977+0.629<.001<.00139
LSCCRASAL3 →+0.664+0.676<.001<.00139
HNSCSEPTIN6_S388 →+0.728+0.661<.001<.00139
LSCCTESPA1_S311 →+1.035+0.566<.001<.00139
Each partner links to its Q-omics profile. Showing the 6 strongest of 25,876 associations by consensus.

SEPTIN6 vs ARHGEF6 — LSCC

Per-sample scatter of SEPTIN6 vs ARHGEF6 in LSCC (Pearson r = 0.85).

Explore this scatter interactively →

Exploration