SEPTIN6

Across TCGA cell cohorts, SEPTIN6 RNA expression is significantly associated with the RNA expression of many other genes, with 12,256 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible SEPTIN6-associated genes across cancer lineages are ZMYM3, WDCP, and UBA1. Each is linked with SEPTIN6 in more than 12 cancer types. Because this analysis shows association rather than direction, both SEPTIN6-to-partner and partner-to-SEPTIN6 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SEPTIN6 versus ZMYM3 in BONE, with a Pearson correlation of 0.78.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SEPTIN6→partner) and Y-score (partner→SEPTIN6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	ZMYM3 →	+1.260	+1.879	<.001	<.001	3	13
SOFT_TISSUE	WDCP →	+0.973	+1.221	<.001	<.001	3	9
BLOOD_Lymphoma	UBA1 →	+0.934	+1.679	<.001	<.001	3	9
BONE	UBE2O →	+0.915	+1.932	.002	.002	2	10
OESOPHAGUS	COQ10A →	+1.520	+1.872	<.001	.002	2	9
LUNG_NSCLC_LUSC	RTF1 →	+1.002	+1.755	<.001	<.001	2	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,256 associations by consensus.

SEPTIN6 vs ZMYM3 — BONE

Explore this scatter interactively →