SEPTIN2

Across TCGA cell cohorts, SEPTIN2 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,733 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible SEPTIN2-associated GO terms across cancer lineages are Peptidyl-serine phosphorylation, Positive regulation of t-circle formation, and Axo-dendritic transport. Each is linked with SEPTIN2 in more than 12 cancer types. Because this analysis shows association rather than direction, both SEPTIN2-to-partner and partner-to-SEPTIN2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Peptidyl-serine phosphorylation grouped by SEPTIN2-low versus SEPTIN2-high in OVARY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SEPTIN2→partner) and Y-score (partner→SEPTIN2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	Peptidyl-serine phosphorylation →	+0.071	+0.973	<.001	<.001	3	13
UPPER_AERODIGESTIVE_TRACT	Positive regulation of t-circle formation →	-0.186	-1.168	.003	<.001	3	13
BREAST	Axo-dendritic transport →	+0.064	+1.017	<.001	<.001	3	13
UPPER_AERODIGESTIVE_TRACT	Mitotic G2/M transition checkpoint →	+0.100	+1.030	.001	.001	3	12
LARGE_INTESTINE	Positive regulation of organelle assembly →	+0.066	+0.846	<.001	<.001	3	12
UPPER_AERODIGESTIVE_TRACT	Phosphatidylinositol metabolic process →	+0.055	+1.074	.001	.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,733 associations by consensus.

Peptidyl-serine phosphorylation by SEPTIN2 expression — OVARY

Explore this box plot interactively →