SEPTIN2

Across TCGA cell cohorts, SEPTIN2 protein abundance is significantly associated with the RNA expression of many other genes, with 3,879 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible SEPTIN2-associated genes across cancer lineages are CYP17A1, TRAPPC2L, and ACR. Each is linked with SEPTIN2 in more than 1 cancer types. Because this analysis shows association rather than direction, both SEPTIN2-to-partner and partner-to-SEPTIN2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SEPTIN2 versus CYP17A1 in BREAST, with a Pearson correlation of -0.87.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SEPTIN2→partner) and Y-score (partner→SEPTIN2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	CYP17A1 →	-0.056	-2.805	.005	.005	3	2
BREAST	TRAPPC2L →	-1.630	-3.396	.001	.001	3	2
LUNG_NSCLC_LUAD	ACR →	-0.160	-2.776	.001	.001	3	1
LUNG_NSCLC_LUAD	SOX5 →	-0.260	-2.693	.002	.001	3	1
LUNG_NSCLC_LUAD	BCR →	-1.023	-2.550	.009	.005	2	2
BREAST	CYTH4 →	-0.366	-2.750	.007	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,879 associations by consensus.

SEPTIN2 vs CYP17A1 — BREAST

Explore this scatter interactively →