SEPTIN14P8

Across TCGA pan-cancer cohorts, SEPTIN14P8 RNA differs between tumor and matched normal tissue in 3 of 18 cancer types tested, making tumor–normal expression one of SEPTIN14P8’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where SEPTIN14P8 RNA is repressed in tumor relative to normal tissue. In most cancer types SEPTIN14P8 is over-expressed in tumor, although a few such as KIRC show the opposite, repressed pattern.

KIRC, PAAD, and KIRP are the cancer types where SEPTIN14P8 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in SEPTIN14P8 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	All	II,III,IV	−0.184	.011	4	view →
PAAD	Female	All	+1.000	.041	2	view →
KIRP	Female	II,III,IV	+0.698	.031	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 3 strongest of 3 lineages.

SEPTIN14P8–KIRC

Open the KIRC breakdown →