SEPTIN14P24

Across TCGA pan-cancer cohorts, SEPTIN14P24 RNA is linked to patient survival in 18 of 34 cancer types, making it the most broadly survival-associated SEPTIN14P24 data layer.

The strongest signal is observed in colon adenocarcinoma (COAD), where higher SEPTIN14P24 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated SEPTIN14P24 expression acts as an unfavorable survival marker, although some lineages such as STAD show a favorable association.

COAD, DLBC, and PAAD are the cancer types where SEPTIN14P24 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
COAD	DFS	Tertile	All	0.391	0.790	<.001	135	view →
DLBC	OS	Tertile	All	0.436	0.902	<.001	90	view →
PAAD	DFS	Tertile	All	0.068	0.484	<.001	72	view →
LUSC	OS	Tertile	III,IV	0.315	0.689	.002	72	view →
HNSC	OS	Tertile	II,III,IV	0.239	0.715	.003	63	view →
STAD	OS	Tertile	IV	1.000	0.246	.006	60	view →
READ	DFS	Tertile	All	0.082	0.845	<.001	36	view →
LAML	DFS	Tertile	All	0.225	0.499	.004	36	view →
KIRP	OS	Tertile	All	0.708	0.892	.013	33	view →
LIHC	OS	Tertile	III,IV	0.184	0.622	.004	27	view →
LGG	OS	Tertile	All	0.430	0.843	<.001	21	view →
BLCA	DFS	Tertile	All	0.147	0.598	.011	18	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 18 lineages.

SEPTIN14P24–COAD (DFS)

Open the COAD breakdown →