SEPTIN14P21

Across TCGA patient cohorts, SEPTIN14P21 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,840 significant associations in total. STAD shows the largest number of these associations.

The most reproducible SEPTIN14P21-associated GO terms across cancer lineages are mRNA 3'-end processing, Regulation of RNA splicing, and Regulation of DNA repair. Each is linked with SEPTIN14P21 in more than 22 cancer types. Because this analysis shows association rather than direction, both SEPTIN14P21-to-partner and partner-to-SEPTIN14P21 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, mRNA 3'-end processing grouped by SEPTIN14P21-low versus SEPTIN14P21-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SEPTIN14P21→partner) and Y-score (partner→SEPTIN14P21) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	mRNA 3'-end processing →	+0.061	+0.103	<.001	<.001	3	23
STAD	Regulation of RNA splicing →	+0.075	+0.104	<.001	<.001	3	23
ESCA	Regulation of DNA repair →	+0.059	+0.110	<.001	.004	3	22
STAD	Nucleotide-excision repair →	+0.056	+0.093	<.001	<.001	3	22
STAD	Protein-DNA complex assembly →	+0.054	+0.108	<.001	<.001	3	22
DLBC	Sex-chromosome dosage compensation →	+0.088	+0.058	<.001	.001	3	22

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,840 associations by consensus.

mRNA 3'-end processing by SEPTIN14P21 expression — STAD

Explore this box plot interactively →