SEPTIN14P2

Across TCGA patient cohorts, SEPTIN14P2 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,065 significant associations in total. PRAD shows the largest number of these associations.

The most reproducible SEPTIN14P2-associated GO terms across cancer lineages are Negative regulation of telomere maintenance, Negative regulation of telomere capping, and Positive regulation of mRNA 3'-end processing. Each is linked with SEPTIN14P2 in more than 13 cancer types. Because this analysis shows association rather than direction, both SEPTIN14P2-to-partner and partner-to-SEPTIN14P2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of telomere maintenance grouped by SEPTIN14P2-low versus SEPTIN14P2-high in THYM.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SEPTIN14P2→partner) and Y-score (partner→SEPTIN14P2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
THYM	Negative regulation of telomere maintenance →	+0.045	+0.081	.004	.004	3	14
PRAD	Negative regulation of telomere capping →	+0.034	+0.210	<.001	<.001	3	13
UCEC	Positive regulation of mRNA 3'-end processing →	+0.049	+0.046	.001	.002	3	12
ACC	Mitochondrial translational elongation →	+0.046	+0.124	.002	.007	3	12
UCEC	Rescue of stalled ribosome →	+0.037	+0.036	.004	.001	3	12
PRAD	Regulation of endoplasmic reticulum tubular network organization →	+0.033	+0.230	<.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,065 associations by consensus.

Negative regulation of telomere maintenance by SEPTIN14P2 expression — THYM

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