SEPTIN14P19

Across TCGA pan-cancer cohorts, SEPTIN14P19 RNA is linked to patient survival in 11 of 34 cancer types, making it the most broadly survival-associated SEPTIN14P19 data layer.

The strongest signal is observed in colon adenocarcinoma (COAD), where higher SEPTIN14P19 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated SEPTIN14P19 expression acts as an unfavorable survival marker, although some lineages such as ESCA and GBM show a favorable association.

COAD, KIRC, and KIRP are the cancer types where SEPTIN14P19 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
COAD	OS	Tertile	III,IV	0.178	0.700	.004	54	view →
KIRC	DFS	Tertile	IV	0.139	0.631	<.001	54	view →
KIRP	OS	Tertile	II,III,IV	0.161	0.771	.002	45	view →
CESC	OS	Tertile	III,IV	0.146	0.657	.015	36	view →
LGG	DFS	Tertile	All	0.498	0.748	<.001	21	view →
KICH	OS	Tertile	II,III,IV	0.216	0.838	.010	18	view →
SKCM	OS	Tertile	IV	0.415	0.861	.014	18	view →
LUSC	OS	Tertile	II,III,IV	0.474	0.738	.019	18	view →
ESCA	OS	Tertile	III,IV	0.641	0.376	.038	18	view →
STAD	OS	Tertile	IV	0.111	0.433	.002	9	view →
GBM	DFS	Tertile	All	0.372	0.215	.045	3	view →

Pink = unfavorable, green = favorable. Showing the 11 strongest of 11 lineages.

SEPTIN14P19–COAD (OS)

Open the COAD breakdown →