SEPTIN11

Across TCGA patient cohorts, SEPTIN11 protein abundance is significantly associated with the RNA expression of many other genes, with 14,621 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible SEPTIN11-associated genes across cancer lineages are SGIP1, PTH1R, and LHFPL6. Each is linked with SEPTIN11 in more than 9 cancer types. Because this analysis shows association rather than direction, both SEPTIN11-to-partner and partner-to-SEPTIN11 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SEPTIN11 versus SGIP1 in CCRCC, with a Pearson correlation of 0.36.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SEPTIN11→partner) and Y-score (partner→SEPTIN11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	SGIP1 →	+0.776	+0.258	.007	<.001	3	10
CCRCC	PTH1R →	+0.966	+0.193	<.001	<.001	3	10
OV	LHFPL6 →	+1.417	+0.448	<.001	<.001	3	10
OV	SYDE1 →	+0.991	+0.411	<.001	<.001	3	9
UCEC	MAPK10 →	+0.810	+0.260	<.001	.009	3	9
OV	FGF1 →	+1.138	+0.343	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,621 associations by consensus.

SEPTIN11 vs SGIP1 — CCRCC

Explore this scatter interactively →