SEPTIN11

Across TCGA cell cohorts, SEPTIN11 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,709 significant associations in total. BONE shows the largest number of these associations.

The most reproducible SEPTIN11-associated GO terms across cancer lineages are Caveolin-mediated endocytosis, Regulation of Golgi inheritance, and Response to oscillatory fluid shear stress. Each is linked with SEPTIN11 in more than 13 cancer types. Because this analysis shows association rather than direction, both SEPTIN11-to-partner and partner-to-SEPTIN11 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Caveolin-mediated endocytosis grouped by SEPTIN11-low versus SEPTIN11-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SEPTIN11→partner) and Y-score (partner→SEPTIN11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Caveolin-mediated endocytosis →	+0.211	+1.231	<.001	.002	3	14
OESOPHAGUS	Regulation of Golgi inheritance →	+0.158	+1.077	<.001	.004	2	13
KIDNEY	Response to oscillatory fluid shear stress →	+0.149	+1.258	<.001	.002	3	12
KIDNEY	Cellular response to oscillatory fluid shear stress →	+0.149	+1.258	<.001	.002	3	12
KIDNEY	Vascular endothelial cell response to oscillatory fluid shear stress →	+0.149	+1.258	<.001	.002	3	12
BREAST	Cell division →	+0.066	+1.547	<.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,709 associations by consensus.

Caveolin-mediated endocytosis by SEPTIN11 expression — BONE

Explore this box plot interactively →