SEPTIN10

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, SEPTIN10 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,891 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible SEPTIN10-associated GO terms across cancer lineages are Negative regulation of mitotic cell cycle phase transition, Regulation of mitotic sister chromatid separation, and Positive regulation of cell cycle process. Each is linked with SEPTIN10 in more than 10 cancer types. Because this analysis shows association rather than direction, both SEPTIN10-to-partner and partner-to-SEPTIN10 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SEPTIN10→partner) and Y-score (partner→SEPTIN10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
KIDNEYNegative regulation of mitotic cell cycle phase transition →+0.049+0.807<.001<.001311
KIDNEYRegulation of mitotic sister chromatid separation →+0.136+0.722.002.001311
CNSPositive regulation of cell cycle process →+0.069+0.690<.001.003310
KIDNEYMicrotubule cytoskeleton organization involved in mitosis →+0.092+0.731<.001.001310
UPPER_AERODIGESTIVE_TRACTRegulation of chromosome separation →+0.111+0.835.006.002211
BLOOD_LymphomaEstablishment or maintenance of microtubule cytoskeleton polarity →+0.198+3.245<.001<.001310
Each partner links to its Q-omics profile. Showing the 6 strongest of 3,891 associations by consensus.

Exploration