SEPHS2

Across TCGA patient cohorts, SEPHS2 RNA expression is significantly associated with the protein abundance of many other proteins, with 12,200 significant associations in total. GBM shows the largest number of these associations.

The most reproducible SEPHS2-associated proteins across cancer lineages are DNAJA3, SBF1, and RBM47. Each is linked with SEPHS2 in more than 6 cancer types. Because this analysis shows association rather than direction, both SEPHS2-to-partner and partner-to-SEPHS2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SEPHS2 versus DNAJA3 in COAD, with a Pearson correlation of 0.36.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SEPHS2→partner) and Y-score (partner→SEPHS2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	DNAJA3 →	+0.364	+0.443	<.001	<.001	3	7
GBM	SBF1 →	-0.281	-0.379	.001	.002	3	6
OV	RBM47 →	+0.510	+0.648	<.001	<.001	3	5
UCEC	CLINT1 →	+0.210	+0.423	.003	.004	3	5
OV	AIFM1 →	+0.609	+0.528	<.001	<.001	3	5
OV	PIP4K2C →	+0.333	+0.481	.001	.003	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,200 associations by consensus.

SEPHS2 vs DNAJA3 — COAD

Explore this scatter interactively →