SEPHS1P7

Across TCGA pan-cancer cohorts, SEPHS1P7 RNA is linked to patient survival in 10 of 34 cancer types, making it the most broadly survival-associated SEPHS1P7 data layer.

The strongest signal is observed in kidney renal papillary cell carcinoma (KIRP), where higher SEPHS1P7 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated SEPHS1P7 expression acts as an unfavorable survival marker.

KIRP, PAAD, and COAD are the cancer types where SEPHS1P7 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRP	DFS	Tertile	II,III,IV	0.145	0.693	<.001	72	view →
PAAD	DFS	Tertile	All	0.076	0.484	<.001	54	view →
COAD	DFS	Tertile	IV	0.035	0.501	<.001	45	view →
BLCA	OS	Tertile	IV	0.120	0.599	<.001	36	view →
LUSC	DFS	Tertile	II,III,IV	0.154	0.673	.006	36	view →
LIHC	OS	Tertile	II,III,IV	0.240	0.779	<.001	30	view →
THCA	OS	Tertile	All	0.567	0.965	<.001	27	view →
SKCM	DFS	Tertile	III,IV	0.204	0.621	<.001	27	view →
OV	DFS	Tertile	III,IV	0.411	0.545	.010	24	view →
LUAD	OS	Tertile	II,III,IV	0.292	0.759	.002	18	view →

Pink = unfavorable, green = favorable. Showing the 10 strongest of 10 lineages.

SEPHS1P7–KIRP (DFS)

Open the KIRP breakdown →