SEPHS1P1

Across TCGA patient cohorts, SEPHS1P1 RNA expression is significantly associated with the protein abundance of many other proteins, with 11,268 significant associations in total. GBM shows the largest number of these associations.

The most reproducible SEPHS1P1-associated proteins across cancer lineages are HNRNPU, DOK3, and EHMT1. Each is linked with SEPHS1P1 in more than 3 cancer types. Because this analysis shows association rather than direction, both SEPHS1P1-to-partner and partner-to-SEPHS1P1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SEPHS1P1 versus HNRNPU in LSCC, with a Pearson correlation of 0.33.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SEPHS1P1→partner) and Y-score (partner→SEPHS1P1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	HNRNPU →	+0.164	+0.479	.007	<.001	3	4
GBM	DOK3 →	-0.452	-0.709	<.001	<.001	3	4
GBM	EHMT1 →	+0.230	+0.716	.007	.002	3	4
OV	FUS →	+0.460	+0.971	.001	.003	3	4
GBM	UNC13D →	-0.597	-1.323	<.001	<.001	3	3
GBM	VASP →	-0.365	-0.783	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,268 associations by consensus.

SEPHS1P1 vs HNRNPU — LSCC

Explore this scatter interactively →