SENP8

Across TCGA patient cohorts, SENP8 RNA expression is significantly associated with the protein abundance of many other proteins, with 14,922 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible SENP8-associated proteins across cancer lineages are MYO9A_S1733, NADK, and FBXO22. Each is linked with SENP8 in more than 4 cancer types. Because this analysis shows association rather than direction, both SENP8-to-partner and partner-to-SENP8 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SENP8 versus MYO9A_S1733 in CCRCC, with a Pearson correlation of 0.54.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SENP8→partner) and Y-score (partner→SENP8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	MYO9A_S1733 →	+0.492	+0.604	<.001	<.001	3	5
GBM	NADK →	-0.336	-0.334	.001	<.001	3	5
BRCA	FBXO22 →	+0.323	+0.345	<.001	<.001	3	5
OV	CPSF7 →	+0.217	+0.251	<.001	.005	3	5
BRCA	FCER1G →	-0.566	-0.341	<.001	<.001	3	5
GBM	THEMIS2 →	-0.314	-0.223	.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,922 associations by consensus.

SENP8 vs MYO9A_S1733 — CCRCC

Explore this scatter interactively →