SENP7

Across TCGA cell cohorts, SENP7 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,546 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible SENP7-associated GO terms across cancer lineages are Positive regulation of organelle assembly, Protein desumoylation, and DNA biosynthetic process. Each is linked with SENP7 in more than 15 cancer types. Because this analysis shows association rather than direction, both SENP7-to-partner and partner-to-SENP7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of organelle assembly grouped by SENP7-low versus SENP7-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SENP7→partner) and Y-score (partner→SENP7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Positive regulation of organelle assembly →	+0.075	+0.826	<.001	.004	3	16
SOFT_TISSUE	Protein desumoylation →	+0.127	+1.075	<.001	<.001	3	15
UPPER_AERODIGESTIVE_TRACT	DNA biosynthetic process →	+0.088	+0.977	<.001	<.001	3	14
UPPER_AERODIGESTIVE_TRACT	Protein localization to vacuole →	+0.067	+0.633	<.001	<.001	3	14
UPPER_AERODIGESTIVE_TRACT	Cytosolic transport →	+0.094	+0.957	<.001	<.001	3	14
UPPER_AERODIGESTIVE_TRACT	Negative regulation of hematopoietic stem cell differentiation →	+0.165	+1.187	<.001	<.001	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,546 associations by consensus.

Positive regulation of organelle assembly by SENP7 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →