SENP3

Across TCGA cell cohorts, SENP3 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,777 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible SENP3-associated GO terms across cancer lineages are Telomere assembly, Mitochondrial large ribosomal subunit assembly, and Regulation of translation at synapse, modulating synaptic transmission. Each is linked with SENP3 in more than 17 cancer types. Because this analysis shows association rather than direction, both SENP3-to-partner and partner-to-SENP3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Telomere assembly grouped by SENP3-low versus SENP3-high in LUNG_NSCLC_LUSC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SENP3→partner) and Y-score (partner→SENP3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	Telomere assembly →	+0.184	+0.990	<.001	.001	3	18
BLOOD_Lymphoma	Mitochondrial large ribosomal subunit assembly →	+0.113	+0.902	<.001	<.001	3	17
LUNG_NSCLC_LUSC	Regulation of translation at synapse, modulating synaptic transmission →	+0.138	+0.885	<.001	<.001	3	16
BLOOD_Lymphoma	Ribosomal large subunit assembly →	+0.110	+0.738	<.001	<.001	3	16
PANCREAS	XMP metabolic process →	+0.133	+0.723	.001	<.001	3	15
PANCREAS	XMP biosynthetic process →	+0.133	+0.723	.001	<.001	3	15

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,777 associations by consensus.

Telomere assembly by SENP3 expression — LUNG_NSCLC_LUSC

Explore this box plot interactively →