SENP2

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, SENP2 RNA expression is significantly associated with the protein abundance of many other proteins, with 17,995 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible SENP2-associated proteins across cancer lineages are FXR1, UBXN7, and IGF2BP2. Each is linked with SENP2 in more than 7 cancer types. Because this analysis shows association rather than direction, both SENP2-to-partner and partner-to-SENP2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SENP2 versus FXR1 in LSCC, with a Pearson correlation of 0.77.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SENP2→partner) and Y-score (partner→SENP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LSCCFXR1 →+0.545+1.103<.001<.00138
LSCCUBXN7 →+0.670+1.093<.001<.00136
LSCCIGF2BP2 →+1.279+0.955<.001<.00136
LSCCPAK2 →+0.344+0.854<.001<.00136
LSCCSDF2 →+0.491+0.663<.001<.00136
LSCCWRNIP1 →+0.339+0.683<.001<.00136
Each partner links to its Q-omics profile. Showing the 6 strongest of 17,995 associations by consensus.

SENP2 vs FXR1 — LSCC

Per-sample scatter of SENP2 vs FXR1 in LSCC (Pearson r = 0.77).

Explore this scatter interactively →

Exploration