SENP2

Across TCGA patient cohorts, SENP2 protein abundance is significantly associated with the RNA expression of many other genes, with 13,638 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible SENP2-associated genes across cancer lineages are CCDC167, AP2M1, and CSTF1. Each is linked with SENP2 in more than 3 cancer types. Because this analysis shows association rather than direction, both SENP2-to-partner and partner-to-SENP2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SENP2 versus CCDC167 in HNSC, with a Pearson correlation of 0.23.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SENP2→partner) and Y-score (partner→SENP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	CCDC167 →	+0.795	+0.542	.009	.003	3	4
LSCC	AP2M1 →	+0.833	+0.475	<.001	<.001	3	4
LSCC	CSTF1 →	+0.396	+0.314	<.001	<.001	3	3
HNSC	DHODH →	+0.753	+0.518	<.001	.002	3	3
LSCC	SSBP1 →	+0.548	+0.532	<.001	<.001	3	3
LSCC	NAT9 →	+0.393	+0.410	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,638 associations by consensus.

SENP2 vs CCDC167 — HNSC

Explore this scatter interactively →