SENP2

Across TCGA cell cohorts, SENP2 mutation is significantly associated with the RNA expression of many other genes, with 3 significant associations in total. CNS shows the largest number of these associations.

The most reproducible SENP2-associated genes across cancer lineages are CCER1, PRAMEF7, and PRAMEF5. Each is linked with SENP2 in more than 1 cancer types. Because this analysis shows association rather than direction, both SENP2-to-partner and partner-to-SENP2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CCER1 grouped by SENP2-low versus SENP2-high in CNS.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SENP2→partner) and Y-score (partner→SENP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CNS	CCER1 →	+0.016	+5.754	<.001	.002	3	1
CNS	PRAMEF7 →	+0.183	+5.754	<.001	.002	3	1
CNS	PRAMEF5 →	+0.459	+5.754	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

CCER1 by SENP2 expression — CNS

Explore this box plot interactively →