SENP1

Across TCGA cell cohorts, SENP1 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,165 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible SENP1-associated GO terms across cancer lineages are Nuclear transport, Nucleocytoplasmic transport, and Regulation of chromosome organization. Each is linked with SENP1 in more than 19 cancer types. Because this analysis shows association rather than direction, both SENP1-to-partner and partner-to-SENP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Nuclear transport grouped by SENP1-low versus SENP1-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SENP1→partner) and Y-score (partner→SENP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Nuclear transport →	+0.091	+0.943	<.001	<.001	3	20
OESOPHAGUS	Nucleocytoplasmic transport →	+0.091	+0.943	<.001	<.001	3	20
BONE	Regulation of chromosome organization →	+0.131	+0.739	.001	<.001	3	19
BONE	Regulation of centrosome cycle →	+0.115	+0.710	.001	.001	3	19
BONE	Centrosome duplication →	+0.141	+0.643	.001	.002	3	19
BONE	Sister chromatid segregation →	+0.157	+0.700	.003	.001	3	19

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,165 associations by consensus.

Nuclear transport by SENP1 expression — OESOPHAGUS

Explore this box plot interactively →