SEMG1

Across TCGA patient cohorts, SEMG1 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,139 significant associations in total. LIHC shows the largest number of these associations.

The most reproducible SEMG1-associated GO terms across cancer lineages are Microvillus organization, Ether biosynthetic process, and Negative regulation of lens fiber cell differentiation. Each is linked with SEMG1 in more than 7 cancer types. Because this analysis shows association rather than direction, both SEMG1-to-partner and partner-to-SEMG1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Microvillus organization grouped by SEMG1-low versus SEMG1-high in ESCA.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SEMG1→partner) and Y-score (partner→SEMG1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ESCA	Microvillus organization →	+0.079	+1.011	<.001	<.001	3	8
ESCA	Ether biosynthetic process →	+0.057	+0.779	<.001	<.001	3	7
ESCA	Negative regulation of lens fiber cell differentiation →	+0.121	+1.122	<.001	<.001	3	7
TGCT	Positive regulation of retinoic acid receptor signaling pathway →	+0.053	+0.224	<.001	.001	3	7
ESCA	Renal system process →	+0.059	+1.194	<.001	<.001	3	7
ESCA	Response to Gram-positive bacterium →	+0.119	+1.066	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,139 associations by consensus.

Microvillus organization by SEMG1 expression — ESCA

Explore this box plot interactively →