SEMG1

Across TCGA cell cohorts, SEMG1 RNA expression is significantly associated with the go_rna of many other GO terms, with 416 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible SEMG1-associated GO terms across cancer lineages are Negative regulation of flagellated sperm motility, Negative regulation of cilium-dependent cell motility, and Negative regulation of cilium movement. Each is linked with SEMG1 in more than 7 cancer types. Because this analysis shows association rather than direction, both SEMG1-to-partner and partner-to-SEMG1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of flagellated sperm motility grouped by SEMG1-low versus SEMG1-high in LARGE_INTESTINE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SEMG1→partner) and Y-score (partner→SEMG1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	Negative regulation of flagellated sperm motility →	+0.591	+1.082	<.001	<.001	3	8
LARGE_INTESTINE	Negative regulation of cilium-dependent cell motility →	+0.591	+1.082	<.001	<.001	3	8
LARGE_INTESTINE	Negative regulation of cilium movement →	+0.591	+1.082	<.001	<.001	3	8
LARGE_INTESTINE	Regulation of serine-type endopeptidase activity →	+0.682	+1.089	<.001	<.001	3	7
LARGE_INTESTINE	Positive regulation of serine-type endopeptidase activity →	+0.682	+1.089	<.001	<.001	3	7
LARGE_INTESTINE	Lipid catabolic process →	+0.029	+0.621	.002	.005	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 416 associations by consensus.

Negative regulation of flagellated sperm motility by SEMG1 expression — LARGE_INTESTINE

Explore this box plot interactively →