SEMA6C

Across TCGA cell cohorts, SEMA6C RNA expression is significantly associated with the RNA expression of many other genes, with 12,278 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible SEMA6C-associated genes across cancer lineages are FAM171A2, POGZ, and VASH1. Each is linked with SEMA6C in more than 17 cancer types. Because this analysis shows association rather than direction, both SEMA6C-to-partner and partner-to-SEMA6C results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SEMA6C versus FAM171A2 in BONE, with a Pearson correlation of 0.76.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SEMA6C→partner) and Y-score (partner→SEMA6C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	FAM171A2 →	+1.588	+1.776	<.001	<.001	3	18
UPPER_AERODIGESTIVE_TRACT	POGZ →	+1.241	+0.971	<.001	.004	1	15
OVARY	VASH1 →	+1.666	+1.526	<.001	<.001	3	13
STOMACH	GPSM1 →	+3.025	+1.459	<.001	<.001	3	13
URINARY_TRACT	SCNN1D →	+1.264	+1.088	<.001	<.001	3	13
STOMACH	NLGN2 →	+2.585	+1.678	<.001	<.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,278 associations by consensus.

SEMA6C vs FAM171A2 — BONE

Explore this scatter interactively →