Across TCGA cell cohorts, SEMA4B RNA expression is significantly associated with the go_rna of many other GO terms, with 5,083 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible SEMA4B-associated GO terms across cancer lineages are Viral process, Fibroblast migration, and Nuclear receptor-mediated signaling pathway. Each is linked with SEMA4B in more than 15 cancer types. Because this analysis shows association rather than direction, both SEMA4B-to-partner and partner-to-SEMA4B results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SEMA4B→partner) and Y-score (partner→SEMA4B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIVER	Viral process →	+0.099	+1.225	.001	.008	2	16
STOMACH	Fibroblast migration →	+0.265	+1.559	<.001	.001	3	14
OVARY	Nuclear receptor-mediated signaling pathway →	+0.093	+1.303	<.001	.007	3	14
UPPER_AERODIGESTIVE_TRACT	Intracellular receptor signaling pathway →	+0.051	+1.554	<.001	.001	3	14
BONE	Negative regulation of cytokine production →	+0.049	+0.931	.003	.005	3	14
STOMACH	Negative regulation of actin filament polymerization →	+0.134	+1.695	<.001	<.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,083 associations by consensus.

Exploration

SEMA4B survival (RNA) · tumor vs normal (RNA) · all SEMA4B data types