Across TCGA cell cohorts, SEMA4A RNA expression is significantly associated with the RNA expression of many other genes, with 10,327 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible SEMA4A-associated genes across cancer lineages are PPFIBP2, GRHL2, and TMPRSS13. Each is linked with SEMA4A in more than 9 cancer types. Because this analysis shows association rather than direction, both SEMA4A-to-partner and partner-to-SEMA4A results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SEMA4A→partner) and Y-score (partner→SEMA4A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	PPFIBP2 →	+2.421	+2.148	<.001	<.001	3	10
URINARY_TRACT	GRHL2 →	+3.470	+1.880	<.001	<.001	3	9
OESOPHAGUS	TMPRSS13 →	+2.443	+2.523	.001	<.001	3	9
LUNG_NSCLC_LUSC	DDR1 →	+2.874	+3.065	<.001	<.001	3	8
BREAST	ALDH3B2 →	+2.900	+1.705	<.001	<.001	3	8
URINARY_TRACT	SYTL1 →	+2.595	+2.368	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,327 associations by consensus.

Exploration

SEMA4A survival (RNA) · tumor vs normal (RNA) · all SEMA4A data types