SEMA3G

Across TCGA patient cohorts, SEMA3G protein abundance is significantly associated with the RNA expression of many other genes, with 1,312 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible SEMA3G-associated genes across cancer lineages are RNA5SP454, C4BPB, and KCNA5. Each is linked with SEMA3G in more than 1 cancer types. Because this analysis shows association rather than direction, both SEMA3G-to-partner and partner-to-SEMA3G results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SEMA3G versus RNA5SP454 in LUAD, with a Pearson correlation of -0.60.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SEMA3G→partner) and Y-score (partner→SEMA3G) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	RNA5SP454 →	-0.603	-1.059	.006	.003	3	2
BRCA	C4BPB →	+1.042	+0.864	<.001	.004	3	2
LSCC	KCNA5 →	+0.502	+0.553	.002	<.001	3	2
BRCA	PPP1R14A →	+1.341	+0.878	<.001	.002	3	2
BRCA	PKIG →	+1.540	+0.832	<.001	.003	3	2
BRCA	ADPRM →	+0.752	+1.117	.002	.008	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,312 associations by consensus.

SEMA3G vs RNA5SP454 — LUAD

Explore this scatter interactively →