SEMA3G

Across TCGA cell cohorts, SEMA3G RNA expression is significantly associated with the go_rna of many other GO terms, with 3,363 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible SEMA3G-associated GO terms across cancer lineages are XMP metabolic process, XMP biosynthetic process, and 'de novo' XMP biosynthetic process. Each is linked with SEMA3G in more than 9 cancer types. Because this analysis shows association rather than direction, both SEMA3G-to-partner and partner-to-SEMA3G results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, XMP metabolic process grouped by SEMA3G-low versus SEMA3G-high in LUNG_SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SEMA3G→partner) and Y-score (partner→SEMA3G) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	XMP metabolic process →	+0.191	+1.280	<.001	<.001	3	10
LUNG_SCLC	XMP biosynthetic process →	+0.191	+1.280	<.001	<.001	3	10
LUNG_SCLC	'de novo' XMP biosynthetic process →	+0.191	+1.280	<.001	<.001	3	10
LARGE_INTESTINE	tRNA aminoacylation for protein translation →	+0.064	+1.080	.003	.001	2	10
BLOOD_Leukemia	Porphyrin-containing compound biosynthetic process →	+0.100	+0.856	<.001	.001	2	10
BLOOD_Leukemia	Tetrapyrrole biosynthetic process →	+0.100	+0.856	<.001	.001	2	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,363 associations by consensus.

XMP metabolic process by SEMA3G expression — LUNG_SCLC

Explore this box plot interactively →