SELPLG

Across TCGA patient cohorts, SELPLG protein abundance is significantly associated with the RNA expression of many other genes, with 6,736 significant associations in total. GBM shows the largest number of these associations.

The most reproducible SELPLG-associated genes across cancer lineages are CSF3R, TMEM97, and DNAJC27. Each is linked with SELPLG in more than 3 cancer types. Because this analysis shows association rather than direction, both SELPLG-to-partner and partner-to-SELPLG results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SELPLG versus CSF3R in PDAC, with a Pearson correlation of 0.46.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SELPLG→partner) and Y-score (partner→SELPLG) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	CSF3R →	+1.163	+0.654	<.001	.001	3	4
LSCC	TMEM97 →	-0.979	-0.519	<.001	<.001	2	4
LSCC	DNAJC27 →	-0.300	-0.374	.009	.004	3	3
BRCA	DDX27 →	-0.699	-0.861	.001	.002	3	3
LSCC	ZNF2 →	-0.387	-0.445	<.001	.001	3	3
BRCA	NDUFAF7 →	-0.502	-0.784	.008	.008	2	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,736 associations by consensus.

SELPLG vs CSF3R — PDAC

Explore this scatter interactively →