SELP

Across TCGA cell cohorts, SELP RNA expression is significantly associated with the go_rna of many other GO terms, with 677 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible SELP-associated GO terms across cancer lineages are Regulation of axon extension, Circadian regulation of gene expression, and Negative regulation of saliva secretion. Each is linked with SELP in more than 4 cancer types. Because this analysis shows association rather than direction, both SELP-to-partner and partner-to-SELP results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of axon extension grouped by SELP-low versus SELP-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SELP→partner) and Y-score (partner→SELP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Regulation of axon extension →	+0.065	+0.024	.008	.008	2	5
BREAST	Circadian regulation of gene expression →	+0.053	+0.021	<.001	.009	3	3
LARGE_INTESTINE	Negative regulation of saliva secretion →	-0.121	-0.168	<.001	.003	3	3
LARGE_INTESTINE	Hard palate morphogenesis →	-0.121	-0.168	<.001	.003	3	3
LARGE_INTESTINE	Mastication →	-0.121	-0.168	<.001	.003	3	3
LARGE_INTESTINE	Learned vocalization behavior →	-0.121	-0.168	<.001	.003	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 677 associations by consensus.

Regulation of axon extension by SELP expression — UPPER_AERODIGESTIVE_TRACT

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