Across TCGA cell cohorts, SELL mutation is significantly associated with the RNA expression of many other genes, with 16 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible SELL-associated genes across cancer lineages are SMYD1, LRIT1, and UCMA. Each is linked with SELL in more than 1 cancer types. Because this analysis shows association rather than direction, both SELL-to-partner and partner-to-SELL results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SELL→partner) and Y-score (partner→SELL) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CNS	SMYD1 →	+1.266	+3.807	<.001	.007	3	1
CNS	LRIT1 →	+0.759	+4.044	<.001	.003	3	1
CNS	UCMA →	+0.165	+4.169	<.001	.008	3	1
SKIN	IL22 →	+0.010	+4.022	<.001	.006	3	1
SKIN	STRA8 →	+0.016	+3.345	.001	.007	3	1
SKIN	PSKH2 →	+0.027	+3.632	<.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 16 associations by consensus.

Exploration

SELL survival (RNA) · tumor vs normal (RNA) · all SELL data types