Across TCGA pan-cancer cohorts, SELENOWP1 RNA differs between tumor and matched normal tissue in 4 of 18 cancer types tested, making tumor–normal expression one of SELENOWP1’s most consistent transcriptional readouts.

The strongest signal is observed in colon adenocarcinoma (COAD), where SELENOWP1 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types SELENOWP1 is over-expressed in tumor, although a few such as PAAD and LUSC show the opposite, repressed pattern.

COAD, PAAD, and LUSC are the cancer types where SELENOWP1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in SELENOWP1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
COAD	Female	All	+1.027	<.001	6	view →
PAAD	Female	All	−0.360	.046	2	view →
LUSC	All	III,IV	−0.345	.003	1	view →
LIHC	Female	All	+0.064	.023	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 4 strongest of 4 lineages.

Exploration

Same gene, other analysis: SELENOWP1 RNA expression & survival · all SELENOWP1 data types