SELENOW

Across TCGA patient cohorts, SELENOW protein abundance is significantly associated with the RNA expression of many other genes, with 7,857 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible SELENOW-associated genes across cancer lineages are SGCA, ESPL1, and PKNOX2. Each is linked with SELENOW in more than 4 cancer types. Because this analysis shows association rather than direction, both SELENOW-to-partner and partner-to-SELENOW results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SELENOW versus SGCA in HNSC, with a Pearson correlation of 0.34.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SELENOW→partner) and Y-score (partner→SELENOW) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	SGCA →	+1.119	+0.387	<.001	<.001	3	5
COAD	ESPL1 →	-0.618	-0.624	.001	<.001	3	5
OV	PKNOX2 →	+0.736	+0.504	<.001	<.001	3	4
OV	MYLK →	+1.091	+0.384	<.001	.005	3	4
CCRCC	CBX7 →	+0.445	+0.272	<.001	.007	3	4
HNSC	CASQ2 →	+2.112	+0.565	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,857 associations by consensus.

SELENOW vs SGCA — HNSC

Explore this scatter interactively →