SELENOW

Across TCGA cell cohorts, SELENOW RNA expression is significantly associated with the go_rna of many other GO terms, with 4,034 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible SELENOW-associated GO terms across cancer lineages are Vesicle budding from membrane, Negative regulation of stem cell proliferation, and Vesicle targeting, to, from or within Golgi. Each is linked with SELENOW in more than 7 cancer types. Because this analysis shows association rather than direction, both SELENOW-to-partner and partner-to-SELENOW results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Vesicle budding from membrane grouped by SELENOW-low versus SELENOW-high in BLOOD_Lymphoma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SELENOW→partner) and Y-score (partner→SELENOW) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	Vesicle budding from membrane →	+0.046	+2.413	<.001	<.001	3	8
SKIN	Negative regulation of stem cell proliferation →	+0.279	+0.975	<.001	<.001	3	7
BONE	Vesicle targeting, to, from or within Golgi →	+0.071	+1.136	<.001	<.001	3	7
LUNG_SCLC	Enzyme-directed rRNA pseudouridine synthesis →	-0.113	-1.282	.004	<.001	3	7
BLOOD_Lymphoma	Positive regulation of cell maturation →	+0.154	+1.525	<.001	<.001	3	6
BREAST	Regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway →	-0.635	-0.672	.004	.006	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,034 associations by consensus.

Vesicle budding from membrane by SELENOW expression — BLOOD_Lymphoma

Explore this box plot interactively →