Across TCGA patient cohorts, SELENOV RNA expression is significantly associated with the protein abundance of many other proteins, with 8,009 significant associations in total. GBM shows the largest number of these associations.

The most reproducible SELENOV-associated proteins across cancer lineages are PLCG2, DNMT3A, and ALOX5. Each is linked with SELENOV in more than 2 cancer types. Because this analysis shows association rather than direction, both SELENOV-to-partner and partner-to-SELENOV results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SELENOV→partner) and Y-score (partner→SELENOV) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	PLCG2 →	-0.391	-0.492	<.001	<.001	3	3
OV	DNMT3A →	+0.517	+0.522	<.001	.001	3	3
GBM	ALOX5 →	-0.837	-0.711	<.001	<.001	3	3
GBM	PBRM1 →	+0.387	+0.978	<.001	<.001	3	3
LSCC	RBM42 →	+0.236	+0.365	<.001	.007	3	3
GBM	UBA2 →	+0.249	+0.565	.004	.002	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,009 associations by consensus.

Exploration

SELENOV survival (RNA) · tumor vs normal (RNA) · all SELENOV data types