SELENOV

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, SELENOV mutation is significantly associated with the RNA expression of many other genes, with 213 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SELENOV-associated genes across cancer lineages are RNA5SP412, RNA5SP413, and RNA5SP422. Each is linked with SELENOV in more than 1 cancer types. Because this analysis shows association rather than direction, both SELENOV-to-partner and partner-to-SELENOV results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SELENOV→partner) and Y-score (partner→SELENOV) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECRNA5SP412 →+0.884+2.967<.001.00232
UCECRNA5SP413 →+2.127+3.499<.001<.00132
UCECRNA5SP422 →+1.663+3.256<.001<.00132
CESCSPACA1 →+0.115+5.418<.001.00531
CESCLYZL1 →+0.056+5.418<.001.00531
CESCAQP7P4 →+0.096+5.539<.001.00431
Each partner links to its Q-omics profile. Showing the 6 strongest of 213 associations by consensus.

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