Across TCGA pan-cancer cohorts, SELENOTP2 RNA differs between tumor and matched normal tissue in 1 of 18 cancer types tested, making tumor–normal expression one of SELENOTP2’s most consistent transcriptional readouts.
The strongest signal is observed in colon adenocarcinoma (COAD), where SELENOTP2 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types SELENOTP2 is over-expressed in tumor.
COAD are the cancer types where SELENOTP2 tumor–normal differential expression is most reproducible.