SELENOTP1

Across TCGA pan-cancer cohorts, SELENOTP1 RNA is linked to patient survival in 20 of 34 cancer types, making it the most broadly survival-associated SELENOTP1 data layer.

The strongest signal is observed in thyroid carcinoma (THCA), where higher SELENOTP1 RNA is associated with better disease-free survival. In most high-consensus cancer types, elevated SELENOTP1 expression acts as an unfavorable survival marker, although some lineages such as THCA and KIRC show a favorable association.

THCA, KIRC, and KIRP are the cancer types where SELENOTP1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
THCA	DFS	Quartile	All	0.941	0.830	.001	34	view →
KIRC	DFS	Tertile	IV	0.800	0.244	<.001	34	view →
KIRP	OS	Median	III,IV	0.887	0.664	.013	23	view →
LUAD	OS	Median	II,III,IV	0.650	0.762	.007	23	view →
SKCM	OS	Quartile	All	0.837	0.722	.006	22	view →
CHOL	OS	Quartile	All	0.093	0.888	<.001	21	view →
LGG	OS	Tertile	All	0.327	0.589	<.001	17	view →
LUSC	OS	Median	All	0.461	0.356	.005	16	view →
MESO	OS	Median	III,IV	0.465	0.669	.018	13	view →
ACC	DFS	Median	II,III,IV	0.574	0.815	.032	11	view →
OV	OS	Quartile	IV	0.835	0.502	.022	8	view →
READ	OS	Quartile	IV	0.628	1.000	.018	8	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 20 lineages.

SELENOTP1–THCA (DFS)

Open the THCA breakdown →