Across TCGA patient cohorts, SELENOT RNA expression is significantly associated with the protein abundance of many other proteins, with 10,412 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible SELENOT-associated proteins across cancer lineages are DHX36, DLG1, and EIF4G1. Each is linked with SELENOT in more than 3 cancer types. Because this analysis shows association rather than direction, both SELENOT-to-partner and partner-to-SELENOT results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SELENOT→partner) and Y-score (partner→SELENOT) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	DHX36 →	+0.404	+0.418	<.001	<.001	3	4
LSCC	DLG1 →	+0.290	+0.359	.001	.001	3	4
LSCC	EIF4G1 →	+0.289	+0.386	<.001	<.001	3	4
OV	ATP13A3 →	+0.586	+0.462	.002	.002	3	3
LSCC	CCNL2_S369 →	-0.287	-0.344	.007	.001	3	3
LSCC	DCUN1D1 →	+0.300	+0.417	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,412 associations by consensus.

Exploration

SELENOT survival (RNA) · tumor vs normal (RNA) · all SELENOT data types