Across TCGA patient cohorts, SELENOT protein abundance is significantly associated with the RNA expression of many other genes, with 7,325 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible SELENOT-associated genes across cancer lineages are NEK3, LRRC2, and F8. Each is linked with SELENOT in more than 2 cancer types. Because this analysis shows association rather than direction, both SELENOT-to-partner and partner-to-SELENOT results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SELENOT→partner) and Y-score (partner→SELENOT) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	NEK3 →	-0.512	-0.380	.003	.001	3	3
HNSC	LRRC2 →	-0.689	-0.331	.007	.001	3	3
HNSC	F8 →	-0.474	-0.350	<.001	<.001	3	3
HNSC	LINC01560 →	-0.503	-0.241	<.001	.004	3	3
CCRCC	SULT1C4 →	-1.181	-0.462	.003	<.001	3	3
LSCC	DNAJB11 →	+0.614	+0.325	<.001	.003	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,325 associations by consensus.

Exploration

SELENOT survival (RNA) · tumor vs normal (RNA) · all SELENOT data types