SELENON

Across TCGA patient cohorts, SELENON protein abundance is significantly associated with the RNA expression of many other genes, with 3,435 significant associations in total. GBM shows the largest number of these associations.

The most reproducible SELENON-associated genes across cancer lineages are CD276, P3H1, and MFGE8. Each is linked with SELENON in more than 3 cancer types. Because this analysis shows association rather than direction, both SELENON-to-partner and partner-to-SELENON results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SELENON versus CD276 in LSCC, with a Pearson correlation of 0.33.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SELENON→partner) and Y-score (partner→SELENON) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	CD276 →	+0.746	+0.374	<.001	<.001	3	4
LSCC	P3H1 →	+0.719	+0.478	<.001	<.001	3	4
PDAC	MFGE8 →	+0.526	+0.412	<.001	.001	3	3
PDAC	LARP6 →	+0.473	+0.393	.002	.005	3	3
LSCC	NXN →	+0.627	+0.408	<.001	<.001	3	3
LSCC	CHST14 →	+0.680	+0.443	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,435 associations by consensus.

SELENON vs CD276 — LSCC

Explore this scatter interactively →