SELENON

Across TCGA patient cohorts, SELENON protein abundance is significantly associated with the protein abundance of many other proteins, with 10,502 significant associations in total. GBM shows the largest number of these associations.

The most reproducible SELENON-associated proteins across cancer lineages are CRTAP, PLOD1, and SERPINH1. Each is linked with SELENON in more than 4 cancer types. Because this analysis shows association rather than direction, both SELENON-to-partner and partner-to-SELENON results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SELENON versus CRTAP in GBM, with a Pearson correlation of 0.42.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SELENON→partner) and Y-score (partner→SELENON) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	CRTAP →	+0.624	+0.525	<.001	<.001	3	5
GBM	PLOD1 →	+0.678	+0.464	<.001	<.001	3	5
GBM	SERPINH1 →	+0.639	+0.467	<.001	<.001	3	5
UCEC	RCN2 →	+0.489	+0.589	<.001	.001	3	4
UCEC	CD276 →	+0.507	+0.552	<.001	.001	3	4
OV	CHPF →	+0.602	+0.388	<.001	<.001	2	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,502 associations by consensus.

SELENON vs CRTAP — GBM

Explore this scatter interactively →