SELENON

Across TCGA patient cohorts, SELENON mutation is significantly associated with the RNA expression of many other genes, with 2,632 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SELENON-associated genes across cancer lineages are CYCSP22, RN7SL344P, and RN7SKP177. Each is linked with SELENON in more than 1 cancer types. Because this analysis shows association rather than direction, both SELENON-to-partner and partner-to-SELENON results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CYCSP22 grouped by SELENON-low versus SELENON-high in READ.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SELENON→partner) and Y-score (partner→SELENON) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
READ	CYCSP22 →	+0.206	+5.421	<.001	.005	3	2
SKCM	RN7SL344P →	+0.122	+2.936	.002	.005	3	2
LUSC	RN7SKP177 →	+0.150	+5.733	<.001	.001	3	2
UCEC	MIR4482 →	+0.678	+1.623	.002	.008	3	2
UCEC	RWDD4 →	+0.506	+2.839	<.001	.001	3	2
UCEC	MFSD14C →	+0.671	+2.169	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,632 associations by consensus.

CYCSP22 by SELENON expression — READ

Explore this box plot interactively →